Hypericum Perforatum ; or Perforated St. John’s Wort (1799–1810)

St. John’s Wort Helps Rid Your Warts and Makes You Smile

St. John’s Wort (Hypericum perforatum) is a flowering plant often used in herbal medicine, particularly for its potential benefits in improving mood and treating mild to moderate depression. Here’s an overview:

Common Uses:

1. Depression and Anxiety:

• May help reduce symptoms of mild to moderate depression.

• Often used as an alternative to prescription antidepressants.

2. Sleep Disorders:

• Sometimes used to address insomnia or other sleep disturbances.

3. Wound Healing:

• Its oil extract is applied topically for burns, wounds, and inflammation.

4. Menopausal Symptoms:

• Can help alleviate mood swings and other symptoms associated with menopause.

Active Compounds:

Hypericin and hyperforin: These may influence mood-regulating neurotransmitters like serotonin, dopamine, and norepinephrine.

Precautions and Interactions:

1. Drug Interactions:

• Can reduce the effectiveness of many medications, including:

• Birth control pills

• Antidepressants (risk of serotonin syndrome)

• Blood thinners (e.g., warfarin)

• HIV medications

• Chemotherapy drugs

2. Photosensitivity:

• May increase sensitivity to sunlight, leading to a higher risk of sunburn.

3. Side Effects:

• Nausea, dizziness, dry mouth, and restlessness in some individuals.

Dosage:

• Commonly available in capsules, tablets, teas, and tinctures.

• Typical dosage: 300 mg of a standardized extract (0.3% hypericin) taken 2–3 times daily.

Note: Always consult a healthcare provider before starting St. John’s Wort, especially if taking other medications or managing chronic conditions.


ST JOHN’S WORT – SHOWN TO IMPROVE MOOD

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