Study of an Ash Tree (1801-1803) John Constable (English, 1776-1837)

Scientific research has explored the health benefits of the Ash tree

Ash Trees

Scientific research has explored the health benefits of the Ash tree (Fraxinus excelsior), revealing a range of pharmacological properties. Here are some key findings from peer-reviewed studies:

1. Anti-Inflammatory Properties

Extracts from Fraxinus excelsior leaves have demonstrated significant anti-inflammatory effects. A study identified compounds such as ligstroside, formoside, and oleoacteoside, which were shown to decrease they secretion of pro-inflammatory cytokines like TNF-α and IL-6 in human monocyte/macrophage cells. Additionally, these compounds increased the expression of the anti-inflammatory IL-10 receptor, suggesting potential therapeutic applications in inflammatory conditions.  

2. Antioxidant Activity

The leaves of Fraxinus excelsior are rich in phenolic compounds, including flavonoids and secoiridoids, which exhibit strong antioxidant properties. These compounds have been shown to scavenge free radicals and reduce oxidative stress, potentially protecting cells from damage and contributing to overall health.  

3. Antimicrobial Effects

Studies have reported that extracts from Fraxinus excelsior exhibit notable antibacterial activity against various bacterial strains, including Staphylococcus aureus and Escherichia coli. The minimum inhibitory concentrations ranged from 62.5 to 1000 μg/mL, suggesting potential as an antimicrobial agent.  

4. Neuroprotective Benefits

Compounds such as oleuropein, found in Fraxinus excelsior, have been studied for their neuroprotective effects. Research indicates that oleuropein can ameliorate memory deficits and protect against neurodegenerative conditions by modulating apoptotic pathways and reducing oxidative stress.  

5. Anti-Obesity Potential

Extracts from Fraxinus excelsior seeds have demonstrated anti-lipase activity, which can inhibit fat absorption and aid in weight management. A study identified ligstroside as a potent pancreatic lipase inhibitor, suggesting its potential in controlling obesity.  

These studies underscore the diverse therapeutic potential of Fraxinus excelsior species. However, it’s essential to consult healthcare professionals before considering any medicinal use of Ash tree extracts.


Here are a few ways to use the Ash Tree


When I say to a parent, “read to a child,”

I don’t want it to sound like medicine.

I want it to sound like chocolate. 
Mem Fox


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